REGENERATIVE MEDICINE IN GLENVIEW · CHICAGO AREA
Support your recovery.
Stay connected to life.
Personalized care for joint pain, select soft-tissue injuries, and the life you want to keep living. Explore nonsurgical options built around your condition, your movement, and your goals.
Active longevity. Joint preservation. Personalized care.
Understanding regenerative medicine
Regenerative medicine studies ways to support, repair, or replace damaged tissues. In joint and tendon care, it includes PRP and certain cell-based approaches. These treatments differ in their evidence, risks, and regulatory status; the term does not mean that an injection will regrow cartilage. HSS explains the treatment categories.
Explore university perspectives on regenerative medicine
At ReGen360, that broader perspective begins with how you move, feel, and live. We evaluate your symptoms, health history, and activity goals to explore whether regenerative care may have a role in your recovery and long-term function.
Active longevity. Joint preservation.
Our goals are to help you pursue comfortable movement, maintain function, and stay engaged in an active life. Recommendations are personalized; results and the evidence supporting different approaches vary.
Your ReGen360 roadmap
Start with your symptoms, health history, movement, and personal goals.
Review suitable options and make an informed decision with your clinician.
Connect treatment with an individualized plan for activity and recovery.
Follow pain, mobility, and the activities that matter to you over time.
The source material and preparation matter. These categories have different procedures and evidence; “regenerative” is not a single standardized treatment.
On a small screen, swipe across the table to compare all options.
| Consideration | PRP | Bone marrow aspirate concentrate (BMAC) | Donor-derived tissue products |
|---|---|---|---|
| Source | Your own blood, processed to concentrate platelets and the growth factors they release. [5] | Your own bone marrow, commonly collected from the pelvis and processed into a concentrate containing cells and signaling proteins. [5] | A broad category that may include placental, amniotic, or umbilical tissue products. |
| What is involved? | Blood collection, PRP preparation and a targeted injection. The care plan can include rehabilitation and follow-up focused on comfort and movement. | Marrow collection, usually with local anesthesia, followed by preparation and targeted injection. Aftercare addresses both the collection site and treated area. | Preparation and administration vary by the specific product. |
| Published clinical benefits | Knee osteoarthritis: An 18-trial meta-analysis reported clinically meaningful pain relief at 3 and 6 months and functional improvement through 12 months versus placebo. [1] A separate cohort reported 12-month response rates of 75.2% for KL grade 2 and 66.5% for grade 3 after three leukocyte-poor PRP injections. [2] | Knee osteoarthritis: A randomized trial reported pain and functional improvements from baseline sustained through 24 months, with outcomes comparable to PRP. [3] Another randomized trial found sustained improvements through 24 months, with more durable pain benefits in mild osteoarthritis compared with hyaluronic acid. [4] | Evidence cannot be generalized across products. Ask for studies on the exact product and use. |
| Safety and aftercare | Discuss temporary soreness, injection precautions, expected response and the follow-up plan with your clinician. | Discuss comfort measures, precautions for marrow collection and injection, and the individualized recovery plan. | Infection, immune reactions, processing, donor screening, and product-specific risks. |
| Regulatory questions | Device clearance does not establish that PRP treats a particular condition effectively. | Using your own cells does not automatically exempt the procedure from FDA oversight. | FDA registration is not product approval; ask for the applicable status and authorized use. |
The cited benefits concern knee osteoarthritis study populations, not measured ReGen360 outcomes. Symptom improvement does not establish cartilage regrowth. Results vary by condition, preparation and patient.
PRP fits ReGen360's personalized approach to joint and selected tendon concerns, with goals of easing symptoms, improving movement and supporting an active life. Published knee research helps inform the discussion of patient selection, preparation and follow-up.
For patients exploring bone marrow-based care, a ReGen360 consultation can connect the published research with the diagnosis, previous treatment and mobility goals. Discuss whether this approach is appropriate and how rehabilitation and follow-up would fit the plan.
Sources: HSS overview of PRP and BMAC; Stanford description of orthobiologic procedures; AAOS stem-cell patient guidance; FDA patient information on regenerative medicine. The FDA warning addresses unapproved products marketed for orthopedic conditions; it should not be interpreted as saying every therapy in the wider field of regenerative medicine has the same status.
For more detail, read our PRP treatment guide.
The science, made simple
The biological rationale for a treatment and proof of benefit in patients are different questions. Current evidence does not establish that injections of PRP, BMAC, or adipose concentrates reliably regrow musculoskeletal tissues. See the HSS discussion of tissue-regrowth evidence.
Cells communicate through biological signals that help coordinate the response to injury. Regenerative research explores ways to influence these processes.
Tissue health, the nature of an injury, and the surrounding biological environment all matter. Understanding them helps guide a condition-specific discussion.
For you, progress is practical: walking more comfortably, moving with confidence, and taking part in the activities that make life yours.
The ReGen360 approach
Your care plan connects what is happening today with what you want to keep doing tomorrow.
Look at the source of discomfort, the tissues involved, and the factors that may be affecting recovery. Your history and examination shape the next step.
Discuss pain, stiffness, strength, and activity limitations. Build goals around the everyday movements and physical activities you want to improve.
Connect care with sustainable activity, recovery habits, and regular reassessment. The aim is to support your ability to remain engaged in the life you enjoy.
Why explore this approach?
Explore whether an in-office treatment is appropriate for your condition and preferences.
Understand potential benefits, risks, alternatives, and costs before deciding.
Build your plan around the movements and activities you want to improve.
Use follow-up visits to review progress and adjust your plan when needed.
Conditions & concerns
Persistent joint pain, stiffness, or selected tendon problems may prompt an evaluation. The diagnosis comes first: evidence for one procedure and condition cannot establish effectiveness for all injuries. Review condition-specific PRP considerations.
JOINT HEALTH
Discomfort or reduced movement that makes stairs, walking, work, or exercise more difficult. Understanding the cause comes first.
Diagnosis-led planningSOFT-TISSUE CONCERNS
Persistent discomfort or limitations following overuse or injury. Your evaluation considers the tissue involved and its effect on your function.
Individual assessmentACTIVITY & RECOVERY
Difficulty returning to sport, fitness, or an active routine. Explore a care plan that fits your current ability and your goals.
Personalized activity goalsBring questions about joint or soft-tissue discomfort affecting the knees, hips, shoulders, elbows, feet, or ankles. The source of pain, the severity of the problem, and the evidence for an option determine what may be appropriate. Some concerns need other care or a specialist referral.
Not sure what is causing your pain?
A personalized consultation is the place to start.
Your visit, step by step
We want you to leave your consultation with a better understanding of your condition and the next step that makes sense for you.
Review your history, examine the area of concern, and determine whether imaging or further assessment is needed.
Discuss options, expected outcomes, risks, recovery needs, and costs. Treatment begins only when there is an appropriate fit.
Your clinician explains the recommended approach, what the appointment involves, and how to prepare. The plan reflects your needs and informed choice.
Receive aftercare guidance and a plan to reassess symptoms, function, and your response.
Recovery & expectations
Recovery depends on the approach, your condition, and your overall health. Your clinician will explain the expected timeline and how progress will be assessed; improvement is not guaranteed.
AFTER TREATMENT
Follow the aftercare guidance for your plan, including any short-term activity changes and symptoms to report.
EARLY RECOVERY
Adjust work, exercise, and daily activity to the guidance for your treatment and diagnosis.
FOLLOW-UP
Discuss changes in pain, movement, and function. Improvement is not always immediate or predictable.
ONGOING CARE
Decide together whether to continue the plan, consider another option, or seek a specialist evaluation.
Do not stop prescribed medication on your own. Ask your clinician about medications, supplements, and return-to-activity guidance before your procedure.
Active longevity. Your way.
From the golf course to the gym, from a morning walk to time with family—your goals give your care a direction.
Patient fit over volume
A consultation may be helpful if pain or reduced function is affecting your activity and you want to understand your options.
Risks vary by procedure and may include pain, bleeding, infection, or tissue injury. Cell and tissue products can carry additional risks. AAOS explains stem-cell treatment risks and the FDA warns about unapproved regenerative products. Ask about the exact product and intended use.
Your clinician will review your medications, relevant medical conditions, and other factors that may affect eligibility or recovery. Some situations call for a different treatment or specialist referral.
Our commitment: clinical suitability, realistic expectations, and transparent recommendations.
A broad field. An individual decision. Explore the differences between treatments, the evidence, and the questions to ask.
Reviewed by Shannon Patel
Clinical Director & Regenerative Medicine Specialist
Evin Koleini, MD
Anesthesiology and Interventional Pain Management
Regenerative Medicine
Regenerative medicine is a broad field that investigates ways to support, repair, or replace damaged tissues. In musculoskeletal care, it includes approaches such as PRP and certain cell-based treatments. These approaches differ in how they work, the evidence supporting them, their risks, and their regulatory status.
The treatment name alone does not establish that it will restore tissue or improve a particular condition. The specific procedure and intended use matter.
PRP concentrates platelets from a blood sample. Cellular treatments involve cells obtained from sources such as bone marrow or other tissues. Bone marrow aspirate concentrate (BMAC) contains a mixture of cells and other components; it is not the same as a purified stem cell product.
These treatments are not interchangeable. Evidence that PRP helps one condition does not prove that a cellular product will help it. Ask what evidence supports the exact treatment for your diagnosis.
FDA status depends on the exact product, how it is processed, and its intended use. There is no blanket FDA approval for regenerative medicine as a category. Using material from your own body does not, by itself, establish that a procedure is exempt from FDA requirements.
FDA warns that the stem cell, exosome, and related products described in its consumer guidance are not approved for orthopedic conditions such as osteoarthritis or tendonitis. Clearance of equipment used to prepare PRP does not establish approval or effectiveness of PRP for a specific joint condition. Ask the clinician to explain the status of the exact treatment proposed.
Candidacy depends on the diagnosis and the specific treatment being considered. Persistent symptoms alone do not establish that an injection is appropriate. An evaluation should consider examination findings, prior treatment, relevant imaging, medical history, and the activities you want to maintain or return to.
Ask how the proposed option compares with rehabilitation and other established treatments, and what evidence applies to someone with your condition.
Regenerative injections should not be presented as a guaranteed way to regrow cartilage or avoid surgery. Pain relief and better function are different outcomes from structural tissue repair. The evidence and likely benefit depend on the treatment and the condition.
For knee osteoarthritis, the RESTORE trial did not find a significant cartilage-volume benefit with PRP compared with saline at 12 months. A treatment discussion should include alternatives and when a surgical opinion may be useful.
Ask what will be used, where it comes from, what evidence supports it for your diagnosis, and what risks and costs are involved. Also ask about its regulatory status, alternatives, and how progress will be measured. A clear explanation should support an informed decision.
Bring your treatment history and questions. Agree on realistic activity goals and a follow-up plan, including what happens if symptoms do not improve.
ReGen360 · 847-243-6041
University perspectives
Learn more about the broader field, tissue repair, and ongoing research through these university resources.
Wake Forest University
School of Medicine
An introduction to the field’s focus on repairing or replacing damaged tissues, and how researchers work across disciplines to move discoveries toward clinical care.
Read the Wake Forest overview (opens in a new tab)school.wakehealth.eduStanford University
School of Medicine
Stanford’s Institute for Stem Cell Biology and Regenerative Medicine explains its research mission and efforts to translate discoveries about cells into new medical therapies.
Explore Stanford’s institute (opens in a new tab)med.stanford.eduHarvard University
Harvard Stem Cell Institute
Harvard’s Musculoskeletal Program studies muscle, tendon, ligament, cartilage, and bone to develop regenerative approaches to injury and disease.
Read about Harvard’s research (opens in a new tab)hsci.harvard.eduThese independent educational resources include research-stage approaches. They do not establish that a particular treatment will work for you or imply university affiliation with or endorsement of ReGen360.
Your next step · Glenview, Illinois
Explore a personalized plan for pain, mobility, and the activities you want to keep enjoying.
This page provides general education. Evidence differs by treatment and diagnosis; a clinical evaluation is needed to determine suitability. References do not imply endorsement of ReGen360.
